Myeloproliferative neoplasms (MPNs) such as polycythemia vera. essential thrombocythemia. primary myelofibrosis and chronic myeloid leukemia have too similar and accurate way to differentiate their is study of genetic disorders in these patients. Philadelphia chromosome is a sure way to definitively diagnose CML. https://www.roneverhart.com/Small-Sebenza-31-Titanium-Carbon-Fiber-Handle-Insingo-CPM-MagnaCut-Blade-Blue-Single-Lug/